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These phytochemicals have strong anti-inflammatory, antioxidant, and cardioprotective qualities and are widely distributed in fruits, vegetables, herbs, spices, and whole grains (4)

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Typically, the synovial membrane is infiltrated with T cells, B cells and macrophages, eliciting a maladaptive response-to-injury in fibroblast-like synoviocytes (FLS) that hyper-proliferate and destroy cartilage and bone (1, 3)

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